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Journal Article 6

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Serratia marcescens 1

Biological aerated filter 1

Degrading bacterium 1

Ibuprofen 1

anti-inflammatory effect 1

coating 1

dissolution 1

dropirenone and ethinylestradiol tablets 1

ibuprofen 1

ibuprofen tablets 1

intrauterine adhesions 1

melt crystallization 1

missed abortion 1

phase separation 1

physical mixture 1

process optimization 1

solid dispersion 1

solution crystallization 1

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The feasibility of coating by cooling crystallization on ibuprofen naked tablets

Fatima Mameri, Ouahiba Koutchoukali, Mohamed Bouhelassa, Anne Hartwig, Leila Nemdili, Joachim Ulrich

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 2,   Pages 211-219 doi: 10.1007/s11705-017-1619-1

Abstract: In this work, we investigated the feasibility of coating by cooling crystallization on ibuprofen “nakedtablets” manufactured by compression.solution, degree of sub-cooling, agitation speed, retention time, and surface properties of the naked ibuprofentablets.

Keywords： coating     solution crystallization     ibuprofen tablets     sucrose    

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Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion

Liyuan Chen, Qifeng Dang, Chengsheng Liu, Jun Chen, Lei Song, Xiguang Chen

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 195-203 doi: 10.1007/s11684-012-0189-3

Abstract:

The purpose of this study was to improve the dissolution rate and anti-inflammatory effect of ibuprofenThe dissolution of ibuprofen in urea was higher than in PEG4000 or mannitol.Solid dispersion-based (SDBT) and conventional (CT) tablets were prepared by the wet granulation methodforms after SD preparation and that ibuprofen and urea do not interact.The dissolution rate and anti-inflammatory effect of ibuprofen were significantly enhanced by the ibuprofen-urea

Keywords： ibuprofen     solid dispersion     physical mixture     dissolution     anti-inflammatory effect    

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Isolation and application of an ibuprofen-degrading bacterium to a biological aerated filter for the

Bingjie Xu, Gang Xue, Xing Yang

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 5, doi: 10.1007/s11783-018-1080-5

Abstract:

• An ibuprofen-degrading strain, Serratia marcescens BL1,

• The effects of various factors on ibuprofen

Keywords： Ibuprofen     Biological aerated filter     Degrading bacterium     Serratia marcescens    

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Preparation of ibuprofen/lipid composite microparticles by supercritical fluid technique

WANG Xia, CHEN Hui, GUO Yanni, SU Yuzhong, WANG Hongtao, LI Jun

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 4,   Pages 361-367 doi: 10.1007/s11705-008-0066-4

Abstract: Using the CO- and N-assisted atomization processes, the production of ibuprofen/lipid composite microparticlesin comparison with that of the unprocessed ibuprofen.The obtained ibuprofen/tripalmitin composite particles with 5% or 20% of ibuprofen (in mass) evidently/tripalmitin composite particles consisting of 20% ibuprofen prepared by the CO-assisted process, andthe same release is obtained from the ibuprofen/tripalmitin composite particles containing 5% ibuprofen
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The study of missed abortion patients treated with dropirenone and ethinylestradiol tablets after curettage

Zhao Xianli,Liu Chaoyang,Tan Hongwei,Zhang Endi

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 13-15

Abstract:

目的：观察稽留流产清宫术后服用屈螺酮炔雌醇片对减轻宫腔粘连发生的效果。方法：选择2013年6月至2014年6月在西北妇女儿童医院（陕西省妇幼保健院）诊断为稽留流产并实施清宫术的患者220例，随机分成观察组和对照组，每组110例。两组患者均在清宫术前服用米非司酮片150 mg和米索前列醇片600 μg治疗，术后常规应用抗生素3天。观察组：清宫术后给予屈螺酮炔雌醇片，每天服用一片，连续3个周期，对照组：患者实施清宫术后不给予屈螺酮炔雌醇片治疗。观察手术时间、胚胎绒毛大小、患者阴道流血持续时间、月经复潮时间、术后2周超声检查子宫内膜以及宫腔镜检查宫腔粘连情况。结果：观察组术后阴道流血天数（（4.98±0.80）天）及月经复潮时间（（28.41±1.61）天）显著少于对照组（P＜0.05）。观察组患者术后子宫内膜厚度（（9.12±1.12） mm）明显高于对照组子宫内膜厚度（（6.23±1.16）mm），两组比较差异有统计学意义（P＜0.05）。观察组的宫腔粘连率显著低于对照组（x2=4.67，P=0.031）。结论：清宫术后口服屈螺酮炔雌醇片是减少稽留流产术后发生宫腔粘连的一种安全有效的方法。

Keywords： missed abortion     intrauterine adhesions     dropirenone and ethinylestradiol tablets    

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Utilizing melt crystallization fundamentals in the development of a new tabletting technology

Ahmed ABOUZEID,Sandra PETERSEN,Joachim ULRICH

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 3,   Pages 346-352 doi: 10.1007/s11705-014-1443-9

Abstract: It is discussed here for its ability to produce coated tablets, by separating the “coating” materialMolten drops of lutrol-ibuprofen mixture are produced using the drop forming technique.Moreover, solidified tablet batches are analyzed for the purity of their coating by measuring the ibuprofen

Keywords： phase separation     melt crystallization     tablets     process optimization    

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Title Author Date Type Operation

The feasibility of coating by cooling crystallization on ibuprofen naked tablets

Fatima Mameri, Ouahiba Koutchoukali, Mohamed Bouhelassa, Anne Hartwig, Leila Nemdili, Joachim Ulrich

Journal Article

Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion

Liyuan Chen, Qifeng Dang, Chengsheng Liu, Jun Chen, Lei Song, Xiguang Chen

Journal Article

Isolation and application of an ibuprofen-degrading bacterium to a biological aerated filter for the

Bingjie Xu, Gang Xue, Xing Yang

Journal Article

Preparation of ibuprofen/lipid composite microparticles by supercritical fluid technique

WANG Xia, CHEN Hui, GUO Yanni, SU Yuzhong, WANG Hongtao, LI Jun

Journal Article

The study of missed abortion patients treated with dropirenone and ethinylestradiol tablets after curettage

Zhao Xianli,Liu Chaoyang,Tan Hongwei,Zhang Endi

Journal Article

Utilizing melt crystallization fundamentals in the development of a new tabletting technology

Ahmed ABOUZEID,Sandra PETERSEN,Joachim ULRICH

Journal Article